Linear B cell epitope prediction for epitope vaccine design against meningococcal disease and their computational validations through physicochemical properties
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چکیده
منابع مشابه
B-cell Epitope Prediction
When a living organism encounters a pathogenic virus ormicrobe, the B cells of the immune system recognize the pathogen’s antigens by their membrane-bound immunoglobulin receptors and, in response, produce antibodies specific to these antigens. The term antigen refers to any entity—a cell, a macromolecular assembly, or a molecule—that may be bound by either a B-cell receptor or an antibody mole...
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The threat of influenza A and B variants via antigenic drift and emerging novel influenza A and B strains in the human population via antigenic shift has spurred research efforts to improve upon current seasonal influenza vaccines. In recent years, a wave of novel technological breakthroughs has lead to the identification of many broadly anti-influenza hemagglutinin (HA) monoclonal antibodies (...
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Vaccination is generally considered to be the most effective method of preventing infectious diseases. All vaccinations work by presenting a foreign antigen to the immune system in order to evoke an immune response. The active agent of a vaccine may be intact but inactivated ('attenuated') forms of the causative pathogens (bacteria or viruses), or purified components of the pathogen that have b...
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ژورنال
عنوان ژورنال: Network Modeling Analysis in Health Informatics and Bioinformatics
سال: 2012
ISSN: 2192-6662,2192-6670
DOI: 10.1007/s13721-012-0019-1